• Physicochemical properties: solubility, pKa, logP, hygroscopicity
• Screening: polymorph, salt, cocrystal, amorphous dispersion
• Solid state/solution stability: heat, humidity, light, pH, oxidation
• Preclinical formulation
• Oral solid dosage form design, development
• Drug/excipient compatibility, stability
• Bioavailability enhancement of new drug candidate substances
• Dosage forms include but not limited to hydrogel matrix, osmotic pump, enteric coated pellets/tablets, etc.
• Development covering both IND and NDA
• Development: wet/dry granulating, tableting, coating,
• Beads drug layering/coating, lyophilization
• Tablets and capsules production lines (5-100kg)
• Bottle and blister packaging lines
• Spray Dried Dispersion (SDD)
• Hot Melt Extrusion (HME)
• Nanosuspensions
• Solid lipid nanoparticles
• Emulsions
• Micro-emulsions
• SMEDDS